Hellstrom-Lindberg.

On the basis of the proportion of reads reporting the mutant allele, the mutations all were heterozygous and within the dominant clone of cellular material . To characterize the spectrum and frequency of SF3B1 mutations in more detail, both in myeloid cancers and additional cancers, we performed targeted resequencing of the gene in 2087 samples . Among 354 individuals with myelodysplastic syndromes, 72 experienced SF3B1 mutations . Mutations were particularly common in patients with subtypes of myelodysplastic syndromes in which ring sideroblasts are a prominent feature, with 53 of 82 patients positive for SF3B1 adjustments. The subtypes represented in these patients included both refractory anemia with ring sideroblasts and refractory cytopenia with multilineage dysplasia and ring sideroblasts .Air pollution: A significant health concern for people living near regional airports Scientists are reporting evidence that air pollution – a well-recognized problem at major airports – might pose a significant but largely overlooked health concern for people living near smaller regional airports. Those airports are becoming an increasingly important element of global air transportation systems. The study, one of only a few to examine airborne pollutants near regional airports, shows that officials should pay out closer attention to these overlooked emissions, which could cause health problems for local residents. It appears online in ACS’ Environmental Technology & Technology, a semi-regular journal. Related StoriesNew prototype surroundings washer reduces presence of pollutants in the atmosphereParticulate matter, NO2 air pollution associated with increased risk of heart attacksChildren subjected to toxic air pollutants at home much more likely to possess lower GPAsIn the new study, Suzanne Paulson and co-workers note that scientists have known for years that aircraft emissions from gasoline burned during takeoffs and landings can have got a serious impact on air quality near main airports.