And Per Aspenberg.

Of these fractures, 625 were associated with main involvement of a trochanter or distal condyle, 238 were associated with implants, and 16 had been pathologic. This last group also included 24 femoral-throat fractures and 9 fractures that were not femoral. After completion of our analysis, we reviewed all the routine radiologic reviews. These reviews talked about a transverse fracture in 23 of the 59 case patients and a fatigue fracture or an atypical fracture design in mere 1 case individual. The rest mentioned only the location of fractures. Prior to the retrieval of registry information, 72 of the 1234 fractures were randomly selected for reclassification by among the authors who was not informed about the prior categorization or the number of atypical fractures in the sample.Approximately two thirds of the sufferers completed induction treatment . Baseline characteristics were well balanced among the procedure groups , except for a higher Karnofsky performance-status score in the MP group than in the MPR-R and MPR organizations. The median age group was 71 years; 111 patients were more than 75 years of age. A high proportion of patients had International Staging System stage III disease . The median duration of follow-up was 30 weeks . Efficacy Progression-free survival was the primary end point. MPR-R significantly prolonged progression-free survival as compared with MPR and MP ; the MPR and MP groups didn’t differ significantly regarding progression-free survival . In a prespecified landmark analysis, lenalidomide maintenance significantly extended progression-free survival right away of maintenance therapy as compared with placebo .